Title
Force pattern characterisation of Caenorhabditis elegans in motion
Abstract
Caenorhabditis elegans is a worm that could be mutated to have different muscle arms, which may generate distinct force patterns when the worm moves. In this paper, an integrated system employing both a novel PDMS device and a visual feedback from the device is reported. The silicone elastomer-based PDMS device consists of arrays of pillars, which form open channels for the worm to move in and bend the pillars in contact. Enabled by a single vision sensor (CCD/CMOS) camera, the computer vision system is able to transform the forces generated by C. elegans, through detecting the deflection of the pillars with sub-pixel accuracy. The experimental results demonstrate that the current vision-based force sensing system is capable of performing robust force measurements at a full 30 Hz with a 1.52 μN resolution. The framework has the potential to significantly facilitate the study on the relationship between muscle arms and force patterns of C. elegans in motion, and thus gives a better understanding of muscle arms development and modelling.
Year
DOI
Venue
2010
10.1504/IJCAT.2010.034742
IJCAT
Keywords
Field
DocType
different muscle arm,distinct force pattern,current vision-based force,c. elegans,integrated system,caenorhabditis elegans,robust force measurement,computer vision system,pdms device,force pattern characterisation,force pattern,mems,computer vision,automation,microelectromechanical systems,worms,image processing,lab on chip,biomechanics
Deflection (engineering),System on a chip,Microelectromechanical systems,Caenorhabditis elegans,Image processing,Control engineering,CMOS,Electronic engineering,Visual servoing,Engineering,Acoustics,Lab-on-a-chip
Journal
Volume
Issue
ISSN
39
1/2/3
0952-8091
Citations 
PageRank 
References 
0
0.34
0
Authors
7
Name
Order
Citations
PageRank
Ali Ghanbari1152.32
Volker Nock201.01
Richard Blaikie300.68
J. Geoffrey Chase437591.29
Xiaoqi Chen54414.91
Christopher E. Hann600.34
Wenhui Wang79219.23