Name
Abstract | ||
|---|---|---|
Mass spectrometry (MS) is widely used for isotopic labeling studies of metabolism and other biological processes. Quantitative applications-e. g. metabolic flux analysis-require tools to correct the raw MS data for the contribution of all naturally abundant isotopes. IsoCor is a software that allows such correction to be applied to any chemical species. Hence it can be used to exploit any isotopic tracer, from well-known (C-13, N-15, O-18, etc) to unusual (Fe-57, Se-77, etc) isotopes. It also provides new features-e. g. correction for the isotopic purity of the tracer-to improve the accuracy of quantitative isotopic studies, and implements an efficient algorithm to process large datasets. Its user-friendly interface makes isotope labeling experiments more accessible to a wider biological community. |
Year | DOI | Venue |
|---|---|---|
2012 | 10.1093/bioinformatics/bts127 | BIOINFORMATICS |
Field | DocType | Volume |
TRACER,Computer science,Isotope,Metabolic flux analysis,Isotopic labeling,Isotopic ratio outlier analysis,Mass spectrometry,Bioinformatics | Journal | 28 |
Issue | ISSN | Citations |
9 | 1367-4803 | 4 |
PageRank | References | Authors |
0.73 | 2 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Pierre Millard | 1 | 13 | 3.05 |
| Fabien Letisse | 2 | 7 | 1.47 |
| Serguei Sokol | 3 | 8 | 1.51 |
| Jean-Charles Portais | 4 | 15 | 3.25 |