Title
BOLD correlates of continuously fluctuating epileptic activity isolated by independent component analysis.
Abstract
Combined EEG/fMRI recordings offer a promising opportunity to detect brain areas with altered BOLD signal during interictal epileptic discharges (IEDs). These areas are likely to represent the irritative zone, which is itself a reflection of the epileptogenic zone. This paper reports on the imaging findings using independent component analysis (ICA) to continuously quantify epileptiform activity in simultaneously acquired EEG and fMRI. Using ICA derived factors coding for the epileptic activity takes into account that epileptic activity is continuously fluctuating with each spike differing in amplitude, duration and maybe topography, including subthreshold epileptic activity besides clear IEDs and may thus increase the sensitivity and statistical power of combined EEG/fMRI in epilepsy.
Year
DOI
Venue
2008
10.1016/j.neuroimage.2008.05.001
NeuroImage
Keywords
DocType
Volume
statistical power,independent component analysis
Journal
42
Issue
ISSN
Citations 
2
1053-8119
9
PageRank 
References 
Authors
0.65
15
9
Name
Order
Citations
PageRank
Kay Jann1899.10
Roland Wiest290.99
Martinus Hauf390.65
Klaus Meyer490.65
Chris Boesch5141.48
Johannes Mathis690.65
G. Schroth7101.01
Thomas Dierks8625.65
Thomas Koenig915112.57