Title
Modeling of synchronized bursting events: the importance on inhomogeneity.
Abstract
Cultured in vitro neuronal networks are known to exhibit synchronized bursting events (SBE), during which most of the neurons in the system spike within a time window of approximately 100 msec. Such phenomena can be obtained in model networks based on Markram-Tsodyks frequency-dependent synapses. In order to account correctly for the detailed behavior of SBEs, several modifications have to be implemented in such models. Random input currents have to be introduced to account for the rising profile of SBEs. Dynamic thresholds and inhomogeneity in the distribution of neuronal resistances enable us to describe the profile of activity within the SBE and the heavy-tailed distributions of interspike intervals and interevent intervals. Thus, we can account for the interesting appearance of Levy distributions in the data.
Year
DOI
Venue
2004
10.1162/0899766042321823
Neural Computation
Keywords
DocType
Volume
interspike interval,heavy-tailed distribution,interesting appearance,rising profile,dynamic threshold,interevent interval,synchronized bursting events,neuronal resistance,markram-tsodyks frequency-dependent synapsis,vitro neuronal network,detailed behavior
Journal
16
Issue
ISSN
Citations 
12
0899-7667
5
PageRank 
References 
Authors
0.58
5
5
Name
Order
Citations
PageRank
Erez Persi1222.49
David Horn225429.05
Vladislav Volman311212.54
Ronen Segev4426.72
Eshel Ben-Jacob517025.37