Paper Info
Title
AUGUSTUS at MediGRID: Adaption of a bioinformatics application to grid computing for efficient genome analysis
Abstract
In past years, researchers from many domains have discovered Grid technology which opens up new possibilities in solving problems that are difficult to handle with traditional cluster computing. With the rapidly increasing number of partially or completely sequenced genomes, computational genome annotation is a particularly challenging task in computational biology. In this paper, we describe how we adapted the gene-finding tool AUGUSTUS to Grid computing in the context of the German MediGRID project. The gridification process starts with providing security requirements and running the application manually using Grid middleware. Afterwards, the application is described as a workflow of successive program executions, which are automatically distributed to appropriate Grid resources by a workflow engine. Finally, we show how a convenient graphical user interface for end users is created by means of a portal framework.
Year
DOI
Venue
2009
10.1016/j.future.2008.05.010
Future Generation Comp. Syst.
Keywords
Field
DocType
grid portal,grid technology,grid computing,challenging task,efficient genome analysis,workflow,appropriate grid resource,traditional cluster computing,computational biology,bioinformatics application,computational genome annotation,gridification,workflow engine,german medigrid project,bioinformatics,grid middleware,cluster computing,gene finding,genome annotation,graphic user interface
Grid computing,End user,Computer science,Graphical user interface,Semantic grid,Bioinformatics,Workflow engine,Workflow management system,Workflow,Computer cluster,Distributed computing
Journal
Volume
Issue
ISSN
25
3
Future Generation Computer Systems
Citations 
PageRank 
References 
3
0.45
12
Authors
5
Name
Order
Citations
PageRank
Dietmar Sommerfeld1445.13
Thomas Lingner234331.15
M Stanke353051.45
B Morgenstern4109790.87
Harald Richter5226.97