Name
Title | ||
|---|---|---|
Constitutive Modelling of Endothelium Denudation for Finite Element Simulation of Angioplasty |
Abstract | ||
|---|---|---|
This study aims at characterizing and modelling the effect of mechanical factors on endothelial denudation during angioplasty, such as normal force between balloon and artery, stretching of arterial walls, and relative displacement between contacting surfaces. Friction damage was applied to porcine aorta samples with different contact forces, relative displacements, and biplanar stretching conditions. After the tests, endothelium denudation was quantified by isolating and counting the remaining endothelial cells. Using multiple-regression analysis, a constitutive model is proposed for integration in finite element software. This model will help optimize balloon and stent deployment conditions to minimize the amount of damage to the endothelium, and eventually to reduce the occurrence of restenosis. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1007/978-3-540-70521-5_3 | ISBMS |
Keywords | Field | DocType |
endothelial denudation,endothelium denudation,constitutive modelling,relative displacement,finite element simulation,constitutive model,arterial wall,optimize balloon,different contact force,friction damage,aorta sample,remaining endothelial cell,multiple regression analysis,finite element,endothelial cell | Biomedical engineering,Restenosis,Balloon,Contact force,Normal force,Angioplasty,Surgery,Materials science,Aorta,Endothelium,Constitutive equation | Conference |
Volume | ISSN | Citations |
5104 | 0302-9743 | 0 |
PageRank | References | Authors |
0.34 | 2 | 3 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Sébastien Delorme | 1 | 54 | 11.03 |
| Rouwayda El-Ayoubi | 2 | 0 | 0.34 |
| Patricia Debergue | 3 | 8 | 2.33 |