Title
Computerized mass detection in whole breast ultrasound images: Reduction of false positives using bilateral subtraction technique
Abstract
The comparison of left and right mammograms is a common technique used by radiologists for the detection and diagnosis of masses. In mammography, computer-aided detection (CAD) schemes using bilateral subtraction technique have been reported. However, in breast ultrasonography, there are no reports on CAD schemes using comparison of left and right breasts. In this study, we propose a scheme of false positive reduction based on bilateral subtraction technique in whole breast ultrasound images. Mass candidate regions are detected by using the information of edge directions. Bilateral breast images are registered with reference to the nipple positions and skin lines. A false positive region is detected based on a comparison of the average gray values of a mass candidate region and a region with the same position and same size as the candidate region in the contralateral breast. In evaluating the effectiveness of the false positive reduction method, three normal and three abnormal bilateral pairs of whole breast images were employed. These abnormal breasts included six masses larger than 5 mm. in diameter. The sensitivity was 83% (5/6) with 13.8 (165/12) false positives per breast before applying the proposed reduction method. By applying the method, false positives were reduced to 4.5 (54/12) per breast without removing a true positive region. This preliminary study indicates that the bilateral subtraction technique is effective for improving the performance of a CAD scheme in whole breast ultrasound images.
Year
DOI
Venue
2007
10.1117/12.709225
Proceedings of SPIE
Keywords
Field
DocType
whole breast ultrasound image,computer-aided detection,bilateral subtraction
Mammography,Breast ultrasonography,Computer-aided diagnosis,Skin lines,Radiology,Whole breast,Subtraction,Medicine,Ultrasound,False positive paradox
Conference
Volume
ISSN
Citations 
6514
0277-786X
3
PageRank 
References 
Authors
0.56
5
7
Name
Order
Citations
PageRank
Yuji Ikedo1365.43
Daisuke Fukuoka2417.37
T Akeshi Hara330.56
Hiroshi Fujita411824.65
Etsuo Takada5164.31
Tokiko Endo6568.59
Takako Morita7177.08