Paper Info
Title
Semantic SenseLab: Implementing the vision of the Semantic Web in neuroscience.
Abstract
Integrative neuroscience research needs a scalable informatics framework that enables semantic integration of diverse types of neuroscience data. This paper describes the use of the Web Ontology Language (OWL) and other Semantic Web technologies for the representation and integration of molecular-level data provided by several of SenseLab suite of neuroscience databases.Based on the original database structure, we semi-automatically translated the databases into OWL ontologies with manual addition of semantic enrichment. The SenseLab ontologies are extensively linked to other biomedical Semantic Web resources, including the Subcellular Anatomy Ontology, Brain Architecture Management System, the Gene Ontology, BIRNLex and UniProt. The SenseLab ontologies have also been mapped to the Basic Formal Ontology and Relation Ontology, which helps ease interoperability with many other existing and future biomedical ontologies for the Semantic Web. In addition, approaches to representing contradictory research statements are described. The SenseLab ontologies are designed for use on the Semantic Web that enables their integration into a growing collection of biomedical information resources.We demonstrate that our approach can yield significant potential benefits and that the Semantic Web is rapidly becoming mature enough to realize its anticipated promises. The ontologies are available online at http://neuroweb.med.yale.edu/senselab/.
Year
DOI
Venue
2010
10.1016/j.artmed.2009.11.003
Artificial Intelligence In Medicine
Keywords
DocType
Volume
semantic senselab,description logic,basic formal ontology,integration,senselab suite,web ontology language,ontology mapping,neuroscience,gene ontology,semantic web technology,semantic web,subcellular anatomy ontology,relation ontology,biomedical semantic web resource,senselab ontology
Journal
48
Issue
ISSN
Citations 
1
1873-2860
4
PageRank 
References 
Authors
0.43
6
8
Name
Order
Citations
PageRank
Matthias Samwald151339.34
Huanhuan Chen2731101.79
Alan Ruttenberg358950.24
Ernest Lim4232.49
Luis Marenco513711.58
P L Miller644593.86
G M Shepherd750873.75
Kei-hoi Cheung866460.65