Name
Abstract | ||
|---|---|---|
We have developed Lynx ( http://lynx.ci.uchicago.edu)-a web-based database and a knowledge extraction engine, supporting annotation and analysis of experimental data and generation of weighted hypotheses on molecular mechanisms contributing to human phenotypes and disorders of interest. Its underlying knowledge base ( LynxKB) integrates various classes of information from >35 public databases and private collections, as well as manually curated data from our group and collaborators. Lynx provides advanced search capabilities and a variety of algorithms for enrichment analysis and network-based gene prioritization to assist the user in extracting meaningful knowledge from LynxKB and experimental data, whereas its service-oriented architecture provides public access to LynxKB and its analytical tools via user-friendly web services and interfaces. |
Year | DOI | Venue |
|---|---|---|
2014 | 10.1093/nar/gkt1166 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
genomics,genes,phenotype,internet,systems integration,search engine | Integrative medicine,Annotation,Experimental data,Biology,Knowledge extraction,Knowledge base,Web service,Database,The Internet,System integration | Journal |
Volume | Issue | ISSN |
42 | D1 | 0305-1048 |
Citations | PageRank | References |
6 | 0.52 | 22 |
Authors | ||
12 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Dinanath Sulakhe | 1 | 183 | 18.55 |
| Sandhya Balasubramanian | 2 | 10 | 1.91 |
| Bingqing Xie | 3 | 23 | 3.23 |
| Bo Feng | 4 | 7 | 0.86 |
| Andrew Taylor | 5 | 6 | 0.52 |
| Sheng Wang | 6 | 265 | 28.52 |
| Eduardo Berrocal | 7 | 6 | 0.52 |
| Utpal Dave | 8 | 7 | 0.87 |
| Xu, Jinbo | 9 | 888 | 66.00 |
| Daniela Börnigen | 10 | 10 | 1.91 |
| T Conrad Gilliam | 11 | 25 | 2.62 |
| N Maltsev | 12 | 239 | 58.35 |