Name
Title | ||
|---|---|---|
DeconMSn: a software tool for accurate parent ion monoisotopic mass determination for tandem mass spectra. |
Abstract | ||
|---|---|---|
DeconMSn accurately determines the monoisotopic mass and charge state of parent ions from high-resolution tandem mass spectrometry data, offering significant improvement for LTQ_FT and LTQ_Orbitrap instruments over the commercially delivered Thermo Fisher Scientifics extract_msn tool. Optimal parent ion mass tolerance values can be determined using accurate mass information, thus improving peptide identifications for high-mass measurement accuracy experiments. For low-resolution data from LCQ and LTQ instruments, DeconMSn incorporates a support-vector-machine-based charge detection algorithm that identifies the most likely charge of a parent species through peak characteristics of its fragmentation pattern. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1093/bioinformatics/btn063 | BIOINFORMATICS |
Keywords | Field | DocType |
algorithms,low resolution,data analysis,mass spectra,ion,analytical chemistry,artificial intelligence,support vector machine,tandem mass spectrometry,high resolution,bioinformatics,ions | Software tool,Data mining,Tandem,Analytical chemistry,Orbitrap,Computer science,Mass spectrum,Tandem mass spectrometry,Monoisotopic mass,Ion | Journal |
Volume | Issue | ISSN |
24 | 7 | 1367-4803 |
Citations | PageRank | References |
3 | 0.64 | 1 |
Authors | ||
7 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Anoop M. Mayampurath | 1 | 40 | 4.15 |
| Navdeep Jaitly | 2 | 2988 | 166.08 |
| Samuel O. Purvine | 3 | 3 | 0.64 |
| Matthew E. Monroe | 4 | 52 | 8.92 |
| Kenneth J. Auberry | 5 | 7 | 1.50 |
| Joshua N. Adkins | 6 | 155 | 17.14 |
| Richard D. Smith | 7 | 376 | 40.47 |