Abstract | ||
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Spatial proteomic profiling of tissue sections provides in situ molecular analysis of proteins and peptides. Analysis and visualization of these high-dimensional data cubes is challenging. We present a methodology for this task based on a novel developed algorithm for the feature identification and reduction step. To show the validity of our approach, we analyzed prostate cancer tissue sections with an adapted kernel-density based clustering algorithm. |
Year | DOI | Venue |
---|---|---|
2008 | 10.1109/CBMS.2008.119 | CBMS |
Keywords | Field | DocType |
prostate cancer tissue section,tissue characterization,high-dimensional data cube,feature identification,spatial proteomic data,reduction step,tissue section,clustering algorithm,situ molecular analysis,spatial proteomic,maldi imaging,biomedical imaging,proteomics,molecular biophysics,kernel,data visualization,clustering,feature extraction,high dimensional data,proteins,cancer,biomarkers,data visualisation,mass spectroscopy,data analysis,kernel density,algorithm design and analysis,clustering algorithms | Data mining,Data visualization,Algorithm design,Proteomics,Visualization,Computer science,Feature extraction,MALDI imaging,Proteomic Profiling,Cluster analysis | Conference |
ISSN | ISBN | Citations |
2372-9198 | 978-0-7695-3165-6 | 0 |
PageRank | References | Authors |
0.34 | 7 | 10 |
Name | Order | Citations | PageRank |
---|---|---|---|
Christian Fuchsberger | 1 | 21 | 4.19 |
Heidi Hübl | 2 | 0 | 0.34 |
Georg Schäfer | 3 | 11 | 1.71 |
Alexandre Pelzer | 4 | 0 | 0.34 |
Georg Bartsch | 5 | 11 | 1.03 |
Helmut Klocker | 6 | 11 | 1.37 |
Nicola Barbarini | 7 | 69 | 5.71 |
Riccardo Bellazzi | 8 | 1313 | 141.89 |
Wolfgang Wieder | 9 | 0 | 0.34 |
Günther Bonn | 10 | 0 | 0.34 |