Paper Info
Title
Automated Indirect Manipulation Of Irregular Shaped Cells With Optical Tweezers For Studying Collective Cell Migration
Abstract
Studying collective migration of cells is currently of considerable interest in biology and medicine leading to possibility of novel diagnosis and treatments. Some cells are highly sensitive to direct laser exposure, which may influence their behavior or even cause photodamage. In addition, manual manipulation of cells is time consuming making it hard to carry out systematic studies that are properly timed to exhibit the desired motility. This paper presents an automated planning approach for precise, collision-free, indirect manipulation of cells with irregular, dynamically changing shapes using Optical Tweezers (OT). We have evaluated the effectiveness of our manipulation approach using physical experiments. We have also carried out an experimental study to demonstrate the effect of the indirect manipulation approach on cell-viability.
Year
DOI
Venue
2013
10.1109/ICRA.2013.6630962
2013 IEEE INTERNATIONAL CONFERENCE ON ROBOTICS AND AUTOMATION (ICRA)
Keywords
Field
DocType
biomechanics,optical tweezers,radiation pressure,lasers,vectors,cell viability,cell motility
Collective cell migration,Nanotechnology,Laser exposure,Optical tweezers,Engineering
Conference
Volume
Issue
ISSN
2013
1
1050-4729
Citations 
PageRank 
References 
2
0.42
9
Authors
6
Name
Order
Citations
PageRank
Sagar Chowdhury1686.48
Atul Thakur21008.22
Chenlu Wang3262.89
Petr Svec4626.68
Wolfgang Losert5898.53
Satyandra K Gupta668777.11