Title
Integrated segmentation and nonrigid registration for application in prostate image-guided radiotherapy.
Abstract
Many current image-guided radiotherapy (IGRT) systems incorporate an in-room cone-beam CT (CBCT) with a radiotherapy linear accelerator for treatment day imaging. Segmentation of key anatomical structures (prostate and surrounding organs) in 3DCBCT images as well as registration between planning and treatment images are essential for determining many important treatment parameters. Due to the image quality of CBCT, previous work typically uses manual segmentation of the soft tissues and then registers the images based on the manual segmentation. In this paper, an integrated automatic segmentation/constrained nonrigid registration is presented, which can achieve these two aims simultaneously. This method is tested using 24 sets of real patient data. Quantitative results show that the automatic segmentation produces results that have an accuracy comparable to manual segmentation, while the registration part significantly outperforms both rigid and non-rigid registration. Clinical application also shows promising results.
Year
DOI
Venue
2010
10.1007/978-3-642-15705-9_7
MICCAI
Keywords
DocType
Volume
manual segmentation,non-rigid registration,treatment day imaging,registration part,integrated segmentation,automatic segmentation,treatment image,important treatment parameter,nonrigid registration,current image-guided radiotherapy,integrated automatic segmentation,prostate image-guided radiotherapy,soft tissue,linear accelerator,image quality,image segmentation
Conference
13
Issue
ISSN
ISBN
Pt 1
0302-9743
3-642-15704-1
Citations 
PageRank 
References 
8
0.60
5
Authors
6
Name
Order
Citations
PageRank
Chao Lu1483.10
Sudhakar Chelikani2605.20
Zhe Chen3718.05
Xenophon Papademetris451648.77
Lawrence H. Staib552663.63
James S. Duncan62973466.48