Name
Abstract | ||
|---|---|---|
Cerenkov luminescence imaging (CLI) is a cost-effective molecular imaging tool for biomedical applications of radiotracers. The introduction of Cerenkov luminescence tomography (CLT) relative to planar CLI can be compared to the development of X-ray CT based on radiography. With CLT, quantitative and localized analysis of a radiopharmaceutical distribution becomes feasible. In this contribution, a feasibility study of in vivo radiopharmaceutical imaging in heterogeneous medium is presented. Coupled with a multimodal in vivo imaging system, this CLT reconstruction method allows precise anatomical registration of the positron probe in heterogeneous tissues and facilitates the more widespread application of radiotracers. Source distribution inside the small animal is obtained from CLT reconstruction. The experimental results demonstrated that CLT can be employed as an available in vivo tomographic imaging of charged particle emitters in a heterogeneous medium. |
Year | DOI | Venue |
|---|---|---|
2011 | 10.1155/2011/641618 | Int. J. Biomedical Imaging |
Keywords | Field | DocType |
cerenkov luminescence tomography,heterogeneous tissue,vivo tomographic imaging,vivo imaging system,heterogeneous medium,cerenkov luminescence imaging,clt reconstruction,cost-effective molecular imaging tool,clt reconstruction method,vivo radiopharmaceutical imaging,bioinformatics,biomedical research | Nuclear medicine,Biomedical engineering,Computer science,In vivo,Radiography,Artificial intelligence,Molecular imaging,Computer vision,Tomographic reconstruction,Luminescence,Tomography,Positron,Preclinical imaging | Journal |
Volume | ISSN | Citations |
2011 | 1687-4196 | 2 |
PageRank | References | Authors |
0.91 | 1 | 6 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Jianghong Zhong | 1 | 2 | 1.25 |
| Chenghu Qin | 2 | 21 | 7.30 |
| Xin Yang | 3 | 249 | 31.55 |
| Shuping Zhu | 4 | 3 | 1.54 |
| Xing Zhang | 5 | 109 | 6.74 |
| Jie Tian | 6 | 1475 | 159.24 |