Abstract | ||
---|---|---|
DNA repair pathways and associated cell-cycle checkpoint factors are critical to normal cellular function. Although the roles of many of the member genes of the DNA repair pathways are well known, little is known about the transcriptional regulation of these genes. We hypothesize that the genes involved in DNA repair processes have a common regulatory control system. To address the hypothesis, we analyzed the word content of promoter sequences for genes in the check point factor pathway. This manuscript reports on our discoveries -- putative nodes of a regulatory network. |
Year | DOI | Venue |
---|---|---|
2010 | 10.1145/1854776.1854877 | BCB |
Keywords | Field | DocType |
normal cellular function,regulatory network node,check point factor pathway,member gene,cell-cycle checkpoint factor,manuscript report,promoter sequence,dna repair pathway,regulatory network,common regulatory control system,dna repair process,transcription regulation,cell cycle checkpoint,control system,dna repair | Transcriptional regulation,Gene,Biology,Node (networking),Bioinformatics,DNA repair,Genetics | Conference |
Citations | PageRank | References |
0 | 0.34 | 4 |
Authors | ||
3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Laura Elnitski | 1 | 57 | 7.86 |
Jens Lichtenberg | 2 | 11 | 5.05 |
Lonnie R. Welch | 3 | 314 | 45.64 |