Name
Title | ||
|---|---|---|
Real time decision support system for diagnosis of rare cancers, trained in parallel, on a graphics processing unit. |
Abstract | ||
|---|---|---|
In the present study a new strategy is introduced for designing and developing of an efficient dynamic Decision Support System (DSS) for supporting rare cancers decision making. The proposed DSS operates on a Graphics Processing Unit (GPU) and it is capable of adjusting its design in real time based on user-defined clinical questions in contrast to standard CPU implementations that are limited by processing and memory constrains. The core of the proposed DSS was a Probabilistic Neural Network classifier and was evaluated on 140 rare brain cancer cases, regarding its ability to predict tumors' malignancy, using a panel of 20 morphological and textural features Generalization was estimated using an external 10-fold cross-validation. The proposed GPU-based DSS achieved significantly higher training speed, outperforming the CPU-based system by a factor that ranged from 267 to 288 times. System design was optimized using a combination of 4 textural and morphological features with 78.6% overall accuracy, whereas system generalization was 73.8%±3.2%. By exploiting the inherently parallel architecture of a consumer level GPU, the proposed approach enables real time, optimal design of a DSS for any user-defined clinical question for improving diagnostic assessments, prognostic relevance and concordance rates for rare cancers in clinical practice. |
Year | DOI | Venue |
|---|---|---|
2012 | 10.1016/j.compbiomed.2011.12.004 | Comp. in Bio. and Med. |
Keywords | DocType | Volume |
proposed dss,rare cancer,proposed gpu-based dss,real time decision support,optimal design,rare brain cancer case,user-defined clinical question,cpu-based system,real time,clinical practice | Journal | 42 |
Issue | ISSN | Citations |
4 | 1879-0534 | 4 |
PageRank | References | Authors |
0.46 | 12 | 7 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Konstantinos Sidiropoulos | 1 | 27 | 4.96 |
| Dimitris Glotsos | 2 | 139 | 12.43 |
| Spiros Kostopoulos | 3 | 55 | 8.73 |
| Panagiota Ravazoula | 4 | 152 | 12.25 |
| Ioannis Kalatzis | 5 | 124 | 14.74 |
| Dionisis Cavouras | 6 | 224 | 22.08 |
| John Stonham | 7 | 30 | 3.63 |