Name
Abstract | ||
|---|---|---|
We propose in this paper a novel approach to the classification of discrete sequences. This approach builds a model fitting some dynamical features deduced from the learning sample. These features are discrete phase-type (PH) distributions. They model the first passage times (FPT) between occurrences of pairs of substrings. The PHit algorithm, an adapted version of the Expectation-Maximization algorithm, is proposed to estimate PH distributions. The most informative pairs of substrings are selected according to the Jensen-Shannon divergence between their class conditional empirical FPT distributions. The selected features are then used in two classification schemes: a maximum a posteriori (MAP) classifier and support vector machines (SVM) with marginalized kernels. Experiments on DNA splicing region detection and on protein sublocalization illustrate that the proposed techniques offer competitive results with smoothed Markov chains or SVM with a spectrum string kernel. |
Year | DOI | Venue |
|---|---|---|
2006 | 10.1007/11871842_12 | Lecture Notes in Computer Science |
Keywords | Field | DocType |
novel approach,discrete phase-type,model fitting,sequence discrimination,proposed technique,phit algorithm,classification scheme,class conditional empirical fpt,phase-type distribution,discrete sequence,ph distribution,expectation-maximization algorithm,jensen shannon divergence,markov chains,expectation maximization,markov chain,phase type distribution,string kernel,support vector machine | Expectation–maximization algorithm,Support vector machine,Jensen–Shannon divergence,Markov chain,Algorithm,Phase-type distribution,Maximum a posteriori estimation,String kernel,String (computer science),Mathematics | Conference |
Volume | ISSN | ISBN |
4212 | 0302-9743 | 3-540-45375-X |
Citations | PageRank | References |
0 | 0.34 | 5 |
Authors | ||
2 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Jérôme Callut | 1 | 45 | 3.35 |
| Pierre Dupont | 2 | 380 | 29.30 |