Abstract | ||
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Abstract: When evaluating sequence similarities among nucleic acids bythe usual methods, statistical significance is often found whenthe biological significance of the similarity is dubious. Wedemonstrate that the known statistical properties of nucleic acidsequences strongly affect the statistical distribution ofsimilarity values when calculated by standard procedures. Wepropose a series of models which account for some of these knownstatistical properties. The utility of the method is... |
Year | DOI | Venue |
---|---|---|
1984 | 10.1093/nar/12.1Part1.215 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
statistical significance,nucleic acid,nucleic acids,statistical distribution | Biological evolution,Biology,Nucleic acid,Bioinformatics,Computational biology,Statistical significance,Genetics | Journal |
Volume | Issue | ISSN |
12 | 1 | 0305-1048 |
Citations | PageRank | References |
10 | 7.08 | 0 |
Authors | ||
4 |
Name | Order | Citations | PageRank |
---|---|---|---|
David J. Lipman | 1 | 1449 | 527.73 |
W. John Wilbur | 2 | 424 | 43.91 |
Temple F. Smith | 3 | 139 | 73.26 |
Michael S. Waterman | 4 | 942 | 125.14 |