Title
Statistical evidence for ancestral correlation patterns.
Abstract
Statistical correlations in DNA sequences are an important source of information for processes of genome evolution. As a special case of such correlations and building up on our previous work, here we study, how short-range correlations in Eukaryotic genomes change under elimination of various classes of repetitive DNA. Our main result is that a residual correlation pattern, common to most mammalian species, emerges under elimination of all repetitive DNA, suggesting features of an ancestral correlation signature. Furthermore, using this general framework, we find classes of repeats, which upon deletion move the correlation pattern towards this residual pattern (simple repeats and SINEs) or away from this residual pattern (LINEs). These findings suggest that the common correlation pattern visible in the mammalian species after repeat elimination can be associated with a common mammalian ancestor.
Year
DOI
Venue
2010
10.1016/j.biosystems.2010.03.006
Biosystems
Keywords
Field
DocType
Short range correlations,Genomic signatures,Repetitive DNA,Processes of genome evolution,Ancestral genomes
Genome,Residual,Repeated sequence,Biology,Genome evolution,Correlation,DNA sequencing,Genetics
Journal
Volume
Issue
ISSN
100
3
0303-2647
Citations 
PageRank 
References 
0
0.34
6
Authors
4
Name
Order
Citations
PageRank
Andrea Kuhn100.34
Manuel Dehnert241.68
Werner E Helm342.02
Marc-Thorsten Hütt49013.65