Abstract | ||
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We consider the structure of the intestinal epithelial tissue and of cell–cell junctions as the biological model inspiring a new class of P systems. First we define the concept of cell polarity, a formal property derived from epithelial cells, which present morphologically and functionally distinct regions of the plasma membrane. Then we show two preliminary results for this new model of computation: on the theoretical side, we show that P systems with cell polarity are computationally (Turing) complete; on the modelling side, we show that the transepithelial movement of glucose from the intestinal lumen into the blood can be described by such a formal system. Finally, we define tissue P systems with cell polarity, where each cell has fixed connections to the neighbouring cells and to the environment, according to both the cell polarity and specific cell–cell junctions. |
Year | DOI | Venue |
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2009 | 10.1017/S0960129509990156 | Mathematical Structures in Computer Science |
Keywords | Field | DocType |
formal property,epithelial cell,biological model,specific cell,cell polarity,neighbouring cell,tissue p system,p system,formal system,cell junction | Combinatorics,Algorithm,Cell biology,Biological modeling,Epithelial tissue,Cell,Membrane,Mathematics,Cell polarity | Journal |
Volume | Issue | ISSN |
19 | 6 | 0960-1295 |
Citations | PageRank | References |
1 | 0.35 | 18 |
Authors | ||
8 |
Name | Order | Citations | PageRank |
---|---|---|---|
Daniela Besozzi | 1 | 391 | 39.10 |
Nadia Busi | 2 | 1030 | 65.70 |
Paolo Cazzaniga | 3 | 235 | 27.16 |
Claudio Ferretti | 4 | 236 | 30.04 |
Alberto Leporati | 5 | 494 | 51.97 |
Giancarlo Mauri | 6 | 2106 | 297.38 |
Dario Pescini | 7 | 274 | 25.92 |
Claudio Zandron | 8 | 655 | 70.02 |