Paper Info
Title
SNP@Domain: a web resource of single nucleotide polymorphisms (SNPs) within protein domain structures and sequences.
Abstract
The single nucleotide polymorphisms ( SNPs) in conserved protein regions have been thought to be strong candidates that alter protein functions. Thus, we have developed SNP@ Domain, a web resource, to identify SNPs within human protein domains. We annotated SNPs from dbSNP with protein structure- based as well as sequence- based domains: ( i) structure- based using SCOP and ( ii) sequence- based using Pfam to avoid conflicts from two domain assignment methodologies. Users can investigate SNPs within protein domains with 2D and 3D maps. We expect this visual annotation of SNPs within protein domains will help scientists select and interpret SNPs associated with diseases. A web interface for the SNP@ Domain is freely available at http://snpnavigator.net/andfromhttp://bioportal.net/.
Year
DOI
Venue
2006
10.1093/nar/gkl323
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
protein domains,protein structure,single nucleotide polymorphism,web interface
Web resource,Protein domain,Annotation,Biology,dbSNP,Single-nucleotide polymorphism,Genetics,SNP,Molecular biology,Protein structure
Journal
Volume
Issue
ISSN
34
Web Server issue
0305-1048
Citations 
PageRank 
References 
6
0.68
22
Authors
6
Name
Order
Citations
PageRank
Areum Han1102.92
Hyo Jin Kang2151.32
Yoobok Cho3332.32
Sung-Hoon Lee4493.82
Young Joo Kim5465.25
Sungsam Gong6926.31