Title
Morpho-functional visualization of dynamic MR-mammography
Abstract
In view of an increasing use of breast MRI supplementing X-ray mammography, the purpose of this study was the development of a method for fast and efficient analysis of dynamic MR image series of the female breast. The image data sets were acquired with a saturation-recovery-turbo-FLASH sequence facilitating the detection of the kinetics of the contrast agent concentration in the whole breast with a high temporal and spatial resolution. In addition, a morphological 3D-FLASH data set was acquired. The dynamic image data sets were analyzed by tracer kinetic modeling in order to describe the physiological processes underlying the contrast enhancement in mathematical terms and thus enable the estimation of functional tissue specific parameters, reflecting the status of microcirculation. To display morphological and functional tissue information simultaneously, a multidimensional real-time visualization system (using 3D-texture mapping) was developed, which enables a practical and intuitive human-computer interface in virtual reality. The spatially differentiated representation of the computed functional tissue parameters superimposed on the anatomical information offers several possibilities: improved discernibility of contrast enhancement, inspection of the data volume in 3D-space and localization of lesions in space and thus fast and more natural recognition of topological coherencies. In a feasibility study, it could be demonstrated that multidimensional visualization of contrast enhancement in virtual reality is practical. Especially, detection and localization of multiple breast lesions may be an important application.
Year
Venue
Keywords
2004
STUDIES IN HEALTH TECHNOLOGY AND INFORMATICS
dynamic MR-mammography,tracer kinetic modeling,vitual reality
Field
DocType
Volume
Computer vision,Mammography,Data set,Virtual reality,Visualization,Computer science,Image Series,Morpho,Breast MRI,Artificial intelligence,Image resolution
Conference
107
Issue
ISSN
Citations 
Pt 2
0926-9630
4
PageRank 
References 
Authors
1.20
0
12
Name
Order
Citations
PageRank
kh englmeier a141.20
g hellwig a282.41
g hellwig a382.41
j griebel b441.20
s delorme c541.20
m siebert a682.41
m siebert a782.41
g brix b841.20
kh englmeier941.20
jurgen griebel1041.54
stefan delorme11225.67
gunnar brix1241.54