Paper Info
Title
Computerized Analysis of Digital Subtraction Angiography: A Tool for Quantitative In-vivo Vascular Imaging.
Abstract
The purpose of our study was to develop a user- independent computerized tool for the automated seg- mentation and quantitative assessment of in vivo- acquired digital subtraction angiography (DSA) images. Vessel enhancement was accomplished based on the concept of image structural tensor. The developed software was tested on a series of DSA images acquired from one animal and two human angiogenesis models. Its performance was evaluated against manually seg- mented images. A receiver's operating characteristic curve was obtained for every image with regard to the different percentages of the image histogram. The area under the mean curve was 0.89 for the experimental angiogenesis model and 0.76 and 0.86 for the two clinical angiogenesis models. The coordinates of the operating point were 8.3% false positive rate and 92.8% true positive rate for the experimental model. Correspondingly for clinical angiogenesis models, the coordinates were 8.6% false positive rate and 89.2% true positive rate and 9.8% false positive rate and 93.8% true positive rate, respectively. A new user- friendly tool for the analysis of vascular networks in DSA images was developed that can be easily used in either experimental or clinical studies. Its main characteristics are robustness and fast and automatic execution.
Year
DOI
Venue
2008
10.1007/s10278-007-9047-2
J. Digital Imaging
Keywords
DocType
Volume
DSA,image processing,quantification,angiogenesis,experimental
Journal
21
Issue
ISSN
Citations 
4
1618-727X
0
PageRank 
References 
Authors
0.34
14
11
Name
Order
Citations
PageRank
George C Kagadis1373.56
Panagiota Spyridonos222217.43
Dimitris Karnabatidis300.34
Athanassios Diamantopoulos400.34
Emmanouil Athanasiadis5357.30
Antonis Daskalakis6708.26
Konstantinos Katsanos700.34
Dionisis Cavouras8214.67
Dimitris Mihailidis941.44
Dimitris Siablis1000.34
George C Nikiforidis11472.98