Name
Title | ||
|---|---|---|
Flexible composition and execution of high performance, high fidelity multiscale biomedical simulations. |
Abstract | ||
|---|---|---|
Multiscale simulations are essential in the biomedical domain to accurately model human physiology. We present a modular approach for designing, constructing and executing multiscale simulations on a wide range of resources, from laptops to petascale supercomputers, including combinations of these. Our work features two multiscale applications, in-stent restenosis and cerebrovascular bloodflow, which combine multiple existing single-scale applications to create a multiscale simulation. These applications can be efficiently coupled, deployed and executed on computers up to the largest (peta) scale, incurring a coupling overhead of 1-10% of the total execution time. |
Year | DOI | Venue |
|---|---|---|
2012 | 10.1098/rsfs.2012.0087 | INTERFACE FOCUS |
Keywords | Field | DocType |
multiscale modelling,blood flow,high performance computing,in-stent restenosis,cerebrovascular bloodflow,distributed computing | High fidelity,Data mining,Coupling,Supercomputer,Computer science,Human physiology,Cell biology,Computational science,Execution time,Modular design,Petascale computing | Journal |
Volume | Issue | ISSN |
3 | SP2 | 2042-8898 |
Citations | PageRank | References |
12 | 0.74 | 21 |
Authors | ||
12 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Derek Groen | 1 | 133 | 20.48 |
| Joris Borgdorff | 2 | 88 | 6.50 |
| C. Bona-Casas | 3 | 45 | 4.76 |
| James Hetherington | 4 | 77 | 9.06 |
| Rupert W. Nash | 5 | 40 | 4.99 |
| Stefan J. Zasada | 6 | 129 | 12.79 |
| Ilya Saverchenko | 7 | 13 | 1.09 |
| Mariusz Mamonski | 8 | 70 | 4.77 |
| Krzysztof Kurowski | 9 | 281 | 27.93 |
| Miguel O. Bernabéu | 10 | 145 | 16.87 |
| Alfons G. Hoekstra | 11 | 770 | 140.05 |
| Peter V. Coveney | 12 | 206 | 32.82 |