Title
Pipeline for tracking neural progenitor cells
Abstract
Automated methods for neural stem cell lineage construction become increasingly important due to the large amount of data produced from time lapse imagery of in vitro cell growth experiments. Segmentation algorithms with the ability to adapt to the problem at hand and robust tracking methods play a key role in constructing these lineages. We present here a tracking pipeline based on learning a dictionary of discriminative image patches for segmentation and a graph formulation of the cell matching problem incorporating topology changes and acknowledging the fact that segmentation errors do occur. A matched filter for detection of mitotic candidates is constructed to ensure that cell division is only allowed in the model when relevant. Potentially the combination of these robust methods can simplify the initiation of cell lineage construction and extraction of statistics.
Year
DOI
Venue
2012
10.1007/978-3-642-36620-8_16
MCV
Keywords
Field
DocType
segmentation algorithm,neural stem cell lineage,robust tracking method,automated method,cell division,robust method,segmentation error,vitro cell growth experiment,cell lineage construction,tracking pipeline,neural progenitor cell
Computer vision,Graph,Pattern recognition,Segmentation,Computer science,Manual annotation,Neural stem cell,Cell lineage,Artificial intelligence,Matched filter,Discriminative model
Conference
Citations 
PageRank 
References 
0
0.34
6
Authors
4
Name
Order
Citations
PageRank
Jacob S. Vestergaard121.77
Anders L. Dahl200.68
Peter Holm35611.62
Rasmus Larsen498889.80