Title | ||
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GenoMiner: a tool for genome-wide search of coding and non-coding conserved sequence tags. |
Abstract | ||
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GenoMiner is a software tool that searches for regions of similarity between user-submitted genome or transcript sequences and user-specified whole genome assemblies. The program then identifies conserved sequence tags (CSTs) in these homologous regions and provides a prediction of their coding or non-coding nature. The analysis is carried out through three steps: (1) definition of sequence regions homologous to the query sequence in the selected target genomes by a fast BLAT alignment; (2) identification of CSTs by a more sensitive BLAST-like alignment between the query and the homologous regions in the target genomes and (3) assessment of the coding or non-coding nature of detected CSTs through the computation of a suitable coding potential score. GenoMiner allows the user to search the query sequence against a number of vertebrate genome assemblies in a single run providing a user-friendly graphical output. |
Year | DOI | Venue |
---|---|---|
2006 | 10.1093/bioinformatics/bti754 | Bioinformatics |
Keywords | Field | DocType |
conserved sequence tag,transcript sequence,user-specified whole genome assembly,gene finding,genome-wide search,genominer software,sequence region,suitable coding potential score,coding sequences,regulatory regions,vertebrate genome assembly,molecular evolution,query sequence,genome-wide similarity search,genome annotation,non-coding nature,user-submitted genome,similarity search | Genome,Software tool,Data mining,Conserved sequence,Computer science,Coding (social sciences),Blat,Software,Bioinformatics | Journal |
Volume | Issue | ISSN |
22 | 4 | 1367-4803 |
Citations | PageRank | References |
3 | 0.45 | 4 |
Authors | ||
7 |
Name | Order | Citations | PageRank |
---|---|---|---|
Tiziana Castrignanò | 1 | 103 | 10.37 |
Paolo D'onorio De Meo | 2 | 84 | 8.28 |
Giorgio Grillo | 3 | 237 | 55.68 |
Sabino Liuni | 4 | 376 | 86.28 |
Flavio Mignone | 5 | 128 | 12.90 |
Ivano Giuseppe Talamo | 6 | 30 | 2.50 |
Graziano Pesole | 7 | 942 | 107.35 |