Title
Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets.
Abstract
As part of a larger experiment investigating serotonergic regulation of female marmoset sexual behavior, this study was designed to (1) advance methods for PET imaging of common marmoset monkey brain, (2) measure normalized FDG uptake as an index of local cerebral metabolic rates for glucose, and (3) study changes induced in this index of cerebral glucose metabolism by chronic treatment of female marmosets with a serotonin 1A receptor (5-HT1A) agonist. We hypothesized that chronic treatment with the 5-HT1A agonist 8-OH-DPAT would alter the glucose metabolism index in dorsal raphe (DR), medial prefrontal cortex (mPFC), medial preoptic area of hypothalamus (mPOA), ventromedial nucleus of hypothalamus (VMH), and field CA1 of hippocampus.
Year
DOI
Venue
2012
10.1016/j.neuroimage.2011.12.065
NeuroImage
Keywords
Field
DocType
Positron emission tomography,Marmoset,Brain,Glucose metabolism,8-OH-DPAT,Serotonin,Female sexual behavior
Serotonergic,Internal medicine,Prefrontal cortex,Psychology,Callithrix,Agonist,Hypothalamus,Marmoset,Hippocampus,Endocrinology,Dorsal raphe nucleus
Journal
Volume
Issue
ISSN
60
1
1053-8119
Citations 
PageRank 
References 
1
0.35
4
Authors
9