Title
The DIEGO Lab Graph Based Gene Normalization System
Abstract
Gene entity normalization, the mapping of a gene mention in free text to a unique identifier, is one of the primary subtasks in the biomedical information extraction pipeline. Gene entity normalization provides many challenges, specifically with the high ambiguity of gene names and the many-to-many relationship between gene names and identifiers. Drawing inspiration from recent work in word sense disambiguation, this paper presents a gene entity normalization system based on entity relationship graphs. This system creates a concept graph from the possible entities and their relationships within a full-text document, and takes advantage of a node ranking algorithm to rank and score each potential candidate entity. This system is a prototype to represent a specific approach to gene normalization, and the results reflect this. However, this system demonstrates that the relationship graph-based approach, an approach grounded in a theoretical basis, can potentially be useful for gene normalization and possibly for the normalization of various biomedical entities.
Year
DOI
Venue
2011
10.1109/ICMLA.2011.140
ICMLA (2)
Keywords
Field
DocType
potential candidate entity,possible entity,gene mention,diego lab graph,gene entity normalization,many-to-many relationship,gene name,gene entity normalization system,gene normalization system,entity relationship graph,various biomedical entity,gene normalization,natural language processing,data model,text analysis,graph theory,information retrieval,information extraction,genetics,entity relationship
Normalization (statistics),Identifier,Computer science,Weak entity,Natural language processing,Artificial intelligence,Gene nomenclature,Unique identifier,Entity–relationship model,Graph theory,Information retrieval,Information extraction,Machine learning
Conference
Citations 
PageRank 
References 
0
0.34
0
Authors
3
Name
Order
Citations
PageRank
Ryan Sullivan11075.71
Robert Leaman291439.98
Graciela Gonzalez362439.60