Paper Info
Title
GxG-Viztool: A program for visualizing gene-gene interactions in genetic association analysis
Abstract
Gene-gene interactions are important factors underlying a common complex trait that is mostly polygenic. While many methods have been proposed to analyze gene-gene interactions in genetic association studies, the interpretation of the identified gene-gene interactions is not straightforward. In order to aid the interpretation of gene-gene interactions, we developed the GxG-Viztool, an executable program for visualizing gene-gene interactions in genetic association analysis. The GxG-Viztool provides an effective way to recognize genotype combinations that enhance/repress a trait and to display polygenic structure of interactions. The GxG-Viztool implements six graphical tools: checkerboard, pairwise checkerboard, forest, funnel, 3D lattice and parallel coordinate plots, which make it effective to recognize certain patterns in gene-gene interactions. It is freely available at http ://bibs. snu. ac. kr/GxG-Viz tool.
Year
DOI
Venue
2012
10.1109/BIBMW.2012.6470249
BIBM Workshops
Keywords
DocType
Citations 
executable program,certain pattern,genotype combination,pairwise checkerboard,polygenic structure,Gene-gene interaction,genetic association study,common complex trait,gene-gene interaction,GxG-Viz tool,genetic association analysis
Conference
0
PageRank 
References 
Authors
0.34
1
6
Name
Order
Citations
PageRank
Sung Young Lee1214.35
Junghyun Namkung2132.69
Minseok Kwon333928.71
Ming D. Li401.01
Kyunga Kim5243.41
Taesung Park649064.41