Title
CysView: protein classification based on cysteine pairing patterns.
Abstract
CysView is a web-based application tool that identifies and classifies proteins according to their disulfide connectivity patterns. It accepts a dataset of annotated protein sequences in various formats and returns a graphical representation of cysteine pairing patterns. CysView displays cysteine patterns for those records in the data with disulfide annotations. It allows the viewing of records grouped by connectivity patterns. CysView's utility as an analysis tool was demonstrated by the rapid and correct classification of scorpion toxin entries from GenPept on the basis of their disulfide pairing patterns. It has proved useful for rapid detection of irrelevant and partial records, or those with incomplete annotations. CysView can be used to support distant homology between proteins. CysView is publicly available at http://research.i2r.a-star.edu.sg/CysView/.
Year
DOI
Venue
2004
10.1093/nar/gkh475
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
prediction,disulfide bond formation,topologies,connectivity,nucleic,web based applications,protein sequence
Scorpion toxin,Cysteine,Biology,Disulfide bond,Pairing,Computational biology,Bioinformatics,Genetics
Journal
Volume
Issue
ISSN
32
SUPnan
0305-1048
Citations 
PageRank 
References 
6
0.68
8
Authors
8
Name
Order
Citations
PageRank
Johann Lenffer1102.03
Paulo Lai281.09
Wafaa El Mejaber360.68
Asif M. Khan417611.19
J L Koh511014.39
Paul T J Tan6131.44
S H Seah77910.51
Vladimir Brusic855163.37