Paper Info
Title
SDPMOD: an automated comparative modeling server for small disulfide-bonded proteins.
Abstract
Small disulfide-bonded proteins (SDPs) are rich sources for therapeutic drugs. Designing drugs from these proteins requires three-dimensional structural information, which is only available for a subset of these proteins. SDPMOD addresses this deficit in structural information by providing a freely available automated comparative modeling service to the research community. For expert users, SDPMOD offers a manual mode that permits the selection of a desired template as well as a semi-automated mode that allows users to select the template from a suggested list. Besides the selection of templates, expert users can edit the target-template alignment, thus allowing further customization of the modeling process. Furthermore, the web service provides model stereochemical quality evaluation using PROCHECK. SDPMOD is freely accessible to academic users via the web interface at http://proline.bic.nus.edu.sg/sdpmod.
Year
DOI
Venue
2004
10.1093/nar/gkh394
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
disulfide bond,internet,web service,drug design,proteins,comparative modeling,conotoxins
World Wide Web,Biology,Disulfide bond,Software,Template,Bioinformatics,Genetics,The Internet,Personalization
Journal
Volume
Issue
ISSN
32
SUPnan
0305-1048
Citations 
PageRank 
References 
3
0.66
3
Authors
5
Name
Order
Citations
PageRank
Lesheng Kong1352.01
Bernett Teck Kwong Lee230.66
Joo Chuan Tong31829.00
Tin Wee Tan456636.14
Shoba Ranganathan568936.60