Title
Quantitative analysis of brain pathology based on MRI and brain atlases - Applications for cerebral palsy.
Abstract
We have developed a new method to provide a comprehensive quantitative analysis of brain anatomy in cerebral palsy patients, which makes use of two techniques: diffusion tensor imaging and automated 3D whole brain segmentation based on our brain atlas and a nonlinear normalization technique (large-deformation diffeomorphic metric mapping). This method was applied to 13 patients and normal controls. The reliability of the automated segmentation revealed close agreement with the manual segmentation. We illustrate some potential applications for individual characterization and group comparison. This technique also provides a framework for determining the impact of various neuroanatomic features on brain functions.
Year
DOI
Venue
2011
10.1016/j.neuroimage.2010.09.061
NeuroImage
Keywords
Field
DocType
nonlinear dynamics,quantitative analysis,brain mapping,magnetic resonance imaging
Brain segmentation,Brain mapping,Computer vision,Diffusion MRI,Brain atlas,Normalization (statistics),Segmentation,Psychology,Cerebral palsy,Artificial intelligence,Pathology,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
54
3
1053-8119
Citations 
PageRank 
References 
8
0.56
8
Authors
13
Name
Order
Citations
PageRank
Andreia Faria12139.18
Alexander Hoon280.56
Elaine Stashinko3281.67
Xin Li453021.45
Hangyi Jiang555031.16
Ameneh Mashayekh680.90
Kazi Akhter737915.75
John T. Hsu8803.76
Kenichi Oishi945623.56
Jiangyang Zhang1053738.34
Michael I Miller113123422.82
Peter van Zijl12109073.41
Susumu Mori1364543.22