Paper Info
Title
Srnamap: Genomic Maps For Small Non-Coding Rnas, Their Regulators And Their Targets In Microbial Genomes
Abstract
Small non-coding RNAs (sRNAs) carry out a variety of biological functions and affect protein synthesis and protein activities in prokaryotes. Recently, numerous sRNAs and their targets were identified in Escherichia coli and in other bacteria. It is crucial to have a comprehensive resource concerning the annotation of small non-coding RNAs in microbial genomes. This work presents an integrated database, namely sRNAMap, to collect the sRNA genes, the transcriptional regulators of sRNAs and the sRNA target genes by integrating a variety of biological databases and by surveying literature. In this resource, we collected 397 sRNAs, 62 regulators/sRNAs and 60 sRNAs/targets in 70 microbial genomes. Additionally, more valuable information of the sRNAs, such as the secondary structure of sRNAs, the expressed conditions of sRNAs, the expression profiles of sRNAs, the transcriptional start sites of sRNAs and the cross-links to other biological databases, are provided for further investigation. Besides, various textual and graphical interfaces were designed and implemented to facilitate the data access in sRNAMap. sRNAMap is available at http://sRNAMap.mbc.nctu.edu.tw/.
Year
DOI
Venue
2009
10.1093/nar/gkn852
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
secondary structure,transcription regulation,non coding rna,transcription start site,escherichia coli,data access,biological database,genome mapping,nucleic
Genome,Gene,Biology,Transfer RNA,Microbial Genomes,Prokaryotic cells,Biological database,Candidate Disease Gene,Genetics,Molecular biology
Journal
Volume
Issue
ISSN
37
Database issue
0305-1048
Citations 
PageRank 
References 
10
0.71
10
Authors
8
Name
Order
Citations
PageRank
Hsi-Yuan Huang11538.27
Heng-yi Chang2100.71
Chih-Hung Chou317611.55
Ching-Ping Tseng4366.80
Shinn-Ying Ho594069.39
Chi-dung Yang6844.79
Yih-wei Ju7100.71
Hsien-Da Huang883563.83