Title
Model-Based Pancreas Segmentation in Portal Venous Phase Contrast-Enhanced CT Images.
Abstract
This study aims to automatically detect and segment the pancreas in portal venous phase contrast-enhanced computed tomography (CT) images. The institutional review board of the University of Erlangen-Nuremberg approved this study and waived the need for informed consent. Discriminative learning is used to build a pancreas tissue classifier incorporating spatial relationships between the pancreas and surrounding organs and vessels. Furthermore, discrete cosine and wavelet transforms are used to build texture features to describe local tissue appearance. Classification is used to guide a constrained statistical shape model to fit the data. The algorithm to detect and segment the pancreas was evaluated on 40 consecutive CT data that were acquired in the portal venous contrast agent phase. Manual segmentation of the pancreas was carried out by experienced radiologists and served as reference standard. Threefold cross validation was performed. The algorithm-based detection and segmentation yielded an average surface distance of 1.7 mm and an average overlap of 61.2 % compared with the reference standard. The overall runtime of the system was 20.4 min. The presented novel approach enables automatic pancreas segmentation in portal venous phase contrast-enhanced CT images which are included in almost every clinical routine abdominal CT examination. Reliable pancreatic segmentation is crucial for computer-aided detection systems and an organ-specific decision support.
Year
DOI
Venue
2013
10.1007/s10278-013-9586-7
J. Digital Imaging
Keywords
Field
DocType
Computed tomography,Segmentation,Computer-assisted detection,Machine learning,Pancreas
Phase contrast microscopy,Computer vision,Computer science,Segmentation,Computed tomography,Artificial intelligence,Radiology,Cross-validation,Reference standards,Pancreas,Radiographic Image Enhancement,Wavelet transform
Journal
Volume
Issue
ISSN
26
6
1618-727X
Citations 
PageRank 
References 
4
0.53
10
Authors
9
Name
Order
Citations
PageRank
Matthias Hammon16712.70
Alexander Cavallaro211114.22
Marius Erdt36917.17
Peter Dankerl441.55
matthias kirschner58410.50
Klaus Drechsler6458.95
Stefan Wesarg721840.03
Michael Uder8146.44
Rolf Janka993.08