Title
Struct-NB: predicting protein-RNA binding sites using structural features.
Abstract
We analyse sequence and structural features of protein-RNA interfaces using RB-147, a non-redundant dataset of protein-RNA complexes extracted from the PDB. We train classifiers using machine learning algorithms to predict protein-RNA interfaces from sequence and structure-derived features of proteins. Our experiments show that Struct-NB, a Naive Bayes classifier that exploits structural features, outperforms its counterparts that use only sequence features to predict protein-RNA binding residues.
Year
DOI
Venue
2010
10.1504/IJDMB.2010.030965
IJDMB
Keywords
DocType
Volume
naive bayes classifier,structural feature,protein-rna binding site,protein-rna binding residue,protein-rna interface,structure-derived feature,protein-RNA interactions,structural features,propensity,protein-rna interactions,protein-rna complex,sequence feature,analyse sequence,non-redundant dataset
Journal
4
Issue
ISSN
Citations 
1
1748-5673
10
PageRank 
References 
Authors
0.71
11
5
Name
Order
Citations
PageRank
Fadi Towfic1394.92
Cornelia Caragea252053.61
David C Gemperline3100.71
Drena Dobbs442335.43
Vasant Honavar53353468.10