Title
The use of a formal sensitivity analysis on epidemic models with immune protection from maternally acquired antibodies
Abstract
Abstract: This paper considers the outcome of a formal sensitivity analysis on a series of epidemic model structures developed to study the population level effects of maternal antibodies. The analysis is used to compare the potential influence of maternally acquired immunity on various age and time domain observations of infection and serology, with and without seasonality. The results of the analysis indicate that time series observations are largely insensitive to variations in the average duration of this protection, and that age related empirical data are likely to be most appropriate for estimating these characteristics.
Year
DOI
Venue
2011
10.1016/j.cmpb.2010.08.019
Computer Methods and Programs in Biomedicine
Keywords
Field
DocType
various age,formal sensitivity analysis,maternal antibody,average duration,potential influence,population level effect,epidemic model structure,immune protection,time domain observation,time series observation,empirical data,epidemic model,sensitivity analysis
Population,Epidemic model,Immunology,Serology,Immune system,Maternally acquired immunity,Medicine,Antibody
Journal
Volume
Issue
ISSN
104
2
1872-7565
Citations 
PageRank 
References 
0
0.34
4
Authors
3
Name
Order
Citations
PageRank
J. D. Chapman100.34
Michael J. Chappell2407.97
N. D. Evans361.37