Title
Multiple structure tracing in 3D electron micrographs.
Abstract
Automatic interpretation of Transmission Electron Micrograph (TEM) volumes is central to advancing current understanding of neural circuitry. In the context of TEM image analysis, tracing 3D neuronal structures is a significant problem. This work proposes a new model using the conditional random field (CRF) framework with higher order potentials for tracing multiple neuronal structures in 3D. The model consists of two key features. First, the higher order CRF cost is designed to enforce label smoothness in 3D and capture rich textures inherent in the data. Second, a technique based on semi-supervised edge learning is used to propagate high confidence structural edges during the tracing process. In contrast to predominantly edge based methods in the TEM tracing literature, this work simultaneously combines regional texture and learnt edge features into a single framework. Experimental results show that the proposed method outperforms more traditional models in tracing neuronal structures from TEM stacks.
Year
DOI
Venue
2011
10.1007/978-3-642-23623-5_77
MICCAI
Keywords
Field
DocType
tem stack,tem image analysis,higher order potential,learnt edge feature,structural edge,semi-supervised edge learning,new model,multiple structure,higher order crf cost,neuronal structure,electron micrographs,multiple neuronal structure,tracing
Conditional random field,Computer vision,Pattern recognition,Computer science,Artificial intelligence,Micrograph,Smoothness,Tracing,CRFS,Electron
Conference
Volume
Issue
ISSN
14
Pt 1
0302-9743
Citations 
PageRank 
References 
7
0.54
8
Authors
3
Name
Order
Citations
PageRank
Vignesh Jagadeesh121712.74
Nhat Vu21004.69
B. S. Manjunath37561783.37