Name
Abstract | ||
|---|---|---|
We modify existing models of bacteriophage growth on an exponentially growing bacterial population by including (1) density dependent phage attack rates and (2) loss to phage due to adsorption to both infected and uninfected bacteria. The effects of these modi. cations on key pharmacokinetic parameters associated with phage therapy are examined. More general phage growth models are explored which account for infection-age of bacteria, bacteria-phage complex formation, and decoupling phage progeny release from host cell lysis. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1137/070704514 | SIAM JOURNAL ON APPLIED MATHEMATICS |
Keywords | DocType | Volume |
phage therapy,infection-age structure,multiple adsorptions,bacteria-phage complex,passive therapy,active therapy,proliferation threshold | Journal | 68 |
Issue | ISSN | Citations |
6 | 0036-1399 | 1 |
PageRank | References | Authors |
0.63 | 0 | 1 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Hal L. Smith | 1 | 111 | 31.87 |