Title
Multi-level clustering support vector machine trees for improved protein local structure prediction.
Abstract
Local protein structure prediction is one of important tasks for bioinformatics research. In order to further enhance the performance of local protein structure prediction, we propose the Multi-level Clustering Support Vector Machine Trees (MLSVMTs). Building on the multi-cluster tree structure, the MLSVMTs model uses multiple SVMs, each of which is customized to learn the unique sequence-to-structure relationship for one cluster. Both the combined 5 x 2 CV F test and the independent test show that the local structure prediction accuracy of MLSVMTs is significantly better than that of one-level K-means clustering, Multi-level clustering and Clustering Support Vector Machines.
Year
DOI
Venue
2014
10.1504/IJDMB.2014.059063
IJDMB
Keywords
DocType
Volume
local protein structure prediction,mlsvmts model,multi-level clustering support vector,improved protein,machine tree,multi-level clustering,vector machine trees mlsvmts,cv f test,multi-cluster tree structure,vector machines,multi-level clustering support,local structure prediction accuracy,clustering support
Journal
9
Issue
ISSN
Citations 
2
1748-5673
0
PageRank 
References 
Authors
0.34
16
4
Name
Order
Citations
PageRank
Wei Zhong1184.48
Jieyue He212818.92
Xiujuan Chen3415.25
Yi Pan42507203.23