Paper Info
Title
Pseudogene.Org: A Comprehensive Database And Comparison Platform For Pseudogene Annotation
Abstract
The Pseudogene.org knowledgebase serves as a comprehensive repository for pseudogene annotation. The definition of a pseudogene varies within the literature, resulting in significantly different approaches to the problem of identification. Consequently, it is difficult to maintain a consistent collection of pseudogenes in detail necessary for their effective use. Our database is designed to address this issue. It integrates a variety of heterogeneous resources and supports a subset structure that highlights specific groups of pseudogenes that are of interest to the research community. Tools are provided for the comparison of sets and the creation of layered set unions, enabling researchers to derive a current 'consensus' set of pseudogenes. Additional features include versatile search, the capacity for robust interaction with other databases, the ability to reconstruct older versions of the database (accounting for changing genome builds) and an underlying object-oriented interface designed for researchers with a minimal knowledge of programming. At the present time, the database contains more than 100 000 pseudogenes spanning 64 prokaryote and 11 eukaryote genomes, including a collection of human annotations compiled from 16 sources.
Year
DOI
Venue
2007
10.1093/nar/gkl851
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
interface design,object oriented,internet,pseudogenes
Pseudogene,Genome,Minimal knowledge,Annotation,Biology,Software,Database,The Internet
Journal
Volume
Issue
ISSN
35
Database-Issue
0305-1048
Citations 
PageRank 
References 
21
2.92
6
Authors
8
Name
Order
Citations
PageRank
John E. Karro1244.40
Yangpan Yan2212.92
Deyou Zheng3212.92
Zhaolei Zhang423719.25
Nicholas Carriero52469475.93
Philip Cayting6253.87
Paul M Harrison7857.04
Mark Gerstein835445.41