Title
HAPLOWSER: a whole-genome haplotype browser for personal genome and metagenome.
Abstract
Haplotype assembly is becoming a very important tool in genome sequencing of human and other organisms. Although haplotypes were previously inferred from genome assemblies, there has never been a comparative haplotype browser that depicts a global picture of whole-genome alignments among haplotypes of different organisms. We introduce a whole-genome HAPLotype brOWSER (HAPLOWSER), providing evolutionary perspectives from multiple aligned haplotypes and functional annotations. Haplowser enables the comparison of haplotypes from metagenomes, and associates conserved regions or the bases at the conserved regions with functional annotations and custom tracks. The associations are quantified for further analysis and presented as pie charts. Functional annotations and custom tracks that are projected onto haplotypes are saved as multiple files in FASTA format. Haplowser provides a user-friendly interface, and can display alignments of haplotypes with functional annotations at any resolution.
Year
DOI
Venue
2009
10.1093/bioinformatics/btp399
BIOINFORMATICS
Field
DocType
Volume
Genome,Computer science,Haplotype,Genomics,Metagenomics,DNA sequencing,FASTA format,Bioinformatics,Personal genomics,Java
Journal
25
Issue
ISSN
Citations 
18
1367-4803
1
PageRank 
References 
Authors
0.39
6
5
Name
Order
Citations
PageRank
Jong Hyun Kim17716.14
Woo-Cheol Kim2375.46
Michael S. Waterman3942125.14
Sanghyun Park472980.64
Lei M Li5625.61