Title
Geometric alignment of 2D gel electrophoresis images using physics-based elastic registration
Abstract
A key technique for protein analysis is the geometric alignment of 2D gel electrophoresis (2-DE) images. We introduce a new hybrid elastic registration approach for 2-DE images, which is based on an analytic solution of the Navier equation. With this approach cross-effects in elastic deformations can be handled, which is important for the registration of 2-DE images. We have successfully applied our approach to register 2-DE gel images of different levels of complexity and have performed a quantitative evaluation of the results. We have also carried out a comparison with a previous hybrid elastic registration scheme.
Year
DOI
Venue
2008
10.1109/ISBI.2008.4541201
Paris
Keywords
Field
DocType
biochemistry,bioelectric phenomena,electrophoresis,gels,image registration,medical image processing,molecular biophysics,proteins,2-DE gel images,2D gel electrophoresis images,Navier equation,elastic deformation,geometric alignment,hybrid elastic registration,physics-based elastic registration,protein analysis,quantitative evaluation,Cross-effects,Gaussian elastic body splines,Gel electrophoresis,Hybrid elastic registration
Two-dimensional gel electrophoresis,Computer vision,Computer science,Artificial intelligence,Analytic solution,Elasticity (economics),Image registration,Geometric alignment
Conference
ISSN
ISBN
Citations 
1945-7928
978-1-4244-2003-2
2
PageRank 
References 
Authors
0.39
10
3
Name
Order
Citations
PageRank
Stefan Wörz125632.58
Marie-luise Winz240.86
Karl Rohr334048.69