Title | ||
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In patient dose reconstruction using a cine acquisition for dynamic arc radiation therapy. |
Abstract | ||
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An amorphous silicon (a-Si) electronic portal imaging device (EPID) was implemented to perform transit in vivo dosimetry for dynamic conformal arc therapy (DCAT). A set of images was acquired for each arc irradiation using the EPID cine acquisition mode, that supplies a frame acquisition rate of one image every 1.66 s, with a monitor unit rate equal to 100 UM/min. In these conditions good signal stability, +/-1% (2SD) evaluated during 3 months, signal reproducibility within +/-0.8% (2SD) and linearity with dose and dose rate within +/-1% (2SD) were obtained. The transit signal, S (t), due to the transmitted radiotherapy beam below a solid phantom, measured by the EPID cine acquisition mode was used to determine, (1) a set of correlation functions, F(w, L), defined as the ratio between S (t) and the dose at half thickness, D (m), measured in solid water phantoms of different thicknesses, w and with square fields of side L, (2) a set of factors, f(d, L), that take into account the different x-ray scatter contribution from the phantom to the S (t) signal as a function of the variation, d, of the air gap between the phantom and the EPID. The reconstruction of the isocenter dose, D (iso), for DCAT was obtained convolving the transit signal values, obtained at different gantry angles, with the respective reconstruction factors determined by a house-made software. The method was applied to a first patient and the results show that the reconstructed D (iso) values can be obtained with an accuracy within +/-5%. In conclusion, it was assessed that an a-Si EPID with the cine acquisition mode is suitable to perform transit in vivo dosimetry for the DCAT therapy. |
Year | DOI | Venue |
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2009 | 10.1007/s11517-009-0456-x | Med. Biol. Engineering and Computing |
Keywords | Field | DocType |
in vivo dosimetry � electronic portal imaging devicedosimetry � radiotherapystereotactic radiotherapy,radiation therapy,correlation function | Nuclear medicine,Biomedical engineering,Reproducibility,Arc (geometry),Linearity,Imaging phantom,Dosimetry,Monitor unit,Radiation therapy,Mathematics,Isocenter | Journal |
Volume | Issue | ISSN |
47 | 4 | 1741-0444 |
Citations | PageRank | References |
4 | 1.48 | 0 |
Authors | ||
15 |
Name | Order | Citations | PageRank |
---|---|---|---|
Angelo Piermattei | 1 | 8 | 3.36 |
Andrea Fidanzio | 2 | 8 | 3.36 |
Luigi Azario | 3 | 8 | 3.36 |
Francesca Greco | 4 | 8 | 3.69 |
Alessandra Mameli | 5 | 4 | 1.48 |
Savino Cilla | 6 | 8 | 3.36 |
Luca Grimaldi | 7 | 4 | 1.48 |
Guido D'Onofrio | 8 | 4 | 1.82 |
Boris Giuseppe Augelli | 9 | 4 | 1.48 |
Gerardina Stimato | 10 | 4 | 1.82 |
Diego Gaudino | 11 | 4 | 1.48 |
Sara Ramella | 12 | 5 | 2.85 |
Rolando D'Angelillo | 13 | 5 | 1.83 |
Francesco Cellini | 14 | 4 | 1.82 |
Lucio Trodella | 15 | 4 | 1.82 |