Title
Fast elastic registration for adaptive radiotherapy.
Abstract
A new method for elastic mono-modal image registration for adaptive fractionated radiotherapy is presented. Elastic registration is a prerequisite for many medical applications in diagnosis, therapy planning, and therapy. Especially for adaptive radiotherapy efficient and accurate registration is required. Therefore, we developed a fast block matching algorithm for robust image registration. Anatomical landmarks are automatically selected at tissue borders and relocated in the frequency domain. A smooth interpolation is calculated by modified thin-plate splines with local impact. The concept of the algorithm allows different handling of different image structures. Thus, more features were included, like handling of discontinuities (e. g. air cavities in the intestinal track or rectum, observable in only one image), which can not be registered in a conventional way. The planning CT as well as delineated structures of target volume and organs at risks are transformed according to deviations observed in daily acquired verification CTs prior each dose fraction. This way, the time consuming repeated delineation, a prerequisite for adaptive radiotherapy, is avoided. The total calculation time is below 5 minutes and the accurateness is higher than voxel precision, which allows to use this tool in the clinical workflow. We present results of prostate, head-and-neck, and paraspinal tumors with verification by manually selected landmarks. We think this registration technique is not only suitable for adaptive radiotherapy, but also for other applications which require fast registration and possibilities to process special structures (e. g. discontinuities) in a different way.
Year
DOI
Venue
2006
10.1007/11866763_75
MICCAI (2)
Keywords
Field
DocType
robust image registration,registration technique,adaptive radiotherapy,different handling,fast registration,accurate registration,different image structure,elastic registration,elastic mono-modal image registration,adaptive fractionated radiotherapy,block matching algorithm,thin plate spline,image registration,frequency domain
Frequency domain,Spline (mathematics),Voxel,Computer vision,Block-matching algorithm,Pattern recognition,Computer science,Interpolation,Artificial intelligence,Translation (geometry),Workflow,Image registration
Conference
Volume
Issue
ISSN
9
Pt 2
0302-9743
ISBN
Citations 
PageRank 
3-540-44727-X
5
0.64
References 
Authors
5
3
Name
Order
Citations
PageRank
Urban Malsch171.18
Christian Thieke2223.21
Rolf Bendl34511.54