Title
DTI mapping of human brain connectivity: statistical fibre tracking and virtual dissection.
Abstract
Several approaches have been used to trace axonal trajectories from diffusion MRI data. If such techniques were first developed in a deterministic framework reducing the diffusion information to one single main direction, more recent approaches emerged that were statistical in nature and that took into account the whole diffusion information. Based on diffusion tensor MRI data coming from normal brains, this paper presents how brain connectivity could be modelled globally by means of a random walk algorithm. The mass of connections thus generated was then virtually dissected to uncover different tracts. Corticospinal, corticobulbar, and corticothalamic tracts, the corpus callosum, the limbic system, several cortical association bundles, the cerebellar peduncles, and the medial lemniscus were all investigated. The results were then displayed in the form of an in vivo brain connectivity atlas. The connectivity pattern and the individual fibre tracts were then compared to known anatomical data; a good matching was found.
Year
DOI
Venue
2003
10.1016/S1053-8119(03)00142-3
NeuroImage
Keywords
DocType
Volume
Fibre tracking,Diffusion tensor imaging,Connectivity,Brain atlas
Journal
19
Issue
ISSN
Citations 
3
1053-8119
83
PageRank 
References 
Authors
13.05
4
7
Name
Order
Citations
PageRank
P Hagmann18313.05
J-P Thiran210115.73
L Jonasson38313.05
pierre vandergheynst451058.37
Stephanie Clarke5166102.10
P Maeder68313.05
R Meuli78313.38