Abstract | ||
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The view “Biology is an informational science” is now widely accepted—certainly catalyzed in part by the success of the Human Genome Project. There are three levels of biological information: 1-dimensional information of DNA, the 3-dimensional information of proteins, and the 4-dimensional (time variant) information of biological systems and networks. The key to deciphering biological information at each of these levels are the global technologies which analyze many genes, DNAs or proteins at one time. I will discuss several new and pioneering global technologies for genomics and proteomics. Information at each of these levels poses striking computational challenges, which will be discussed. The importance of the need for intimate interactions between biologists, computer scientists and mathematicians will also be discussed, as well as a new approach for teaching biology that may be effective for cross-disciplinary communication. |
Year | DOI | Venue |
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2000 | 10.1145/332306.332363 | RECOMB |
Keywords | Field | DocType |
3 dimensional,biological systems,1 dimensional,gumbel distribution,statistical significance,4 dimensional,sequence alignment | Data science,Gene,Proteomics,Computer science,Genomics,Bioinformatics,Human genome,Genetics | Conference |
ISBN | Citations | PageRank |
1-58113-186-0 | 0 | 0.34 |
References | Authors | |
0 | 1 |
Name | Order | Citations | PageRank |
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Leroy Hood | 1 | 165 | 45.56 |