Name
Title | ||
|---|---|---|
Computer-Aided Nidus Segmentation And Angiographic Characterization Of Arteriovenous Malformations |
Abstract | ||
|---|---|---|
Exact knowledge about the nidus of an arteriovenous malformation (AVM) and the connected vessels is often required for image-based research projects and optimal therapy planning. The aim of this work is to present and evaluate a computer-aided nidus segmentation technique and subsequent angiographic characterization of the connected vessels that can be visualized in 3D.The proposed method was developed and evaluated based on 15 datasets of patients with an AVM. Each dataset consists of a high-resolution 3D and a 4D magnetic resonance angiography (MRA) image sequence. After automatic cerebrovascular segmentation from the 3D MRA dataset, a voxel-wise support vector machine classification based on four extracted features is performed to generate a new parameter map. The nidus is represented by positive values in this parameter map and can be extracted using volume growing. Finally, the nidus segmentation is dilated and used for an automatic identification of feeding arteries and draining veins by integrating hemodynamic information from the 4D MRA datasets.A quantitative comparison of the computer-aided AVM nidus segmentation results to manual gold-standard segmentations by two observers revealed a mean Dice coefficient of 0.835, which is comparable to the inter-observer agreement for which a mean Dice coefficient of 0.830 was determined. The angiographic characterization was visually rated feasible for all patients.The presented computer-aided method enables a reproducible and fast extraction of the AVM nidus as well as an automatic angiographic characterization of the connected vessels, which can be used to support image-based research projects and therapy planning of AVMs. |
Year | DOI | Venue |
|---|---|---|
2013 | 10.1007/s11548-013-0823-9 | INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY |
Keywords | Field | DocType |
Intracranial arteriovenous malformations, Magnetic resonance angiography, Hemodynamics, Computer-assisted image interpretation | Segmentation,Computer-aided,Arteriovenous malformation,Magnetic resonance angiography,Radiology,Intracranial Arteriovenous Malformations,Therapy planning,Medicine | Journal |
Volume | Issue | ISSN |
8 | 5 | 1861-6410 |
Citations | PageRank | References |
4 | 0.55 | 2 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Nils Daniel Forkert | 1 | 26 | 15.30 |
| Till Illies | 2 | 17 | 4.24 |
| Einar Goebell | 3 | 4 | 0.55 |
| Jens Fiehler | 4 | 39 | 20.12 |
| Dennis Säring | 5 | 23 | 9.74 |
| Heinz Handels | 6 | 1527 | 239.84 |