Title
Adrenal gland abnormality detection using random forest classification.
Abstract
Adrenal abnormalities are commonly identified on computed tomography (CT) and are seen in at least 5 % of CT examinations of the thorax and abdomen. Previous studies have suggested that evaluation of Hounsfield units within a region of interest or a histogram analysis of a region of interest can be used to determine the likelihood that an adrenal gland is abnormal. However, the selection of a region of interest can be arbitrary and operator dependent. We hypothesize that segmenting the entire adrenal gland automatically without any human intervention and then performing a histogram analysis can accurately detect adrenal abnormality. We use the random forest classification framework to automatically perform a pixel-wise classification of an entire CT volume (abdomen and pelvis) into three classes namely right adrenal, left adrenal, and background. Once we obtain this classification, we perform histogram analysis to detect adrenal abnormality. The combination of these methods resulted in a sensitivity and specificity of 80 and 90 %, respectively, when analyzing 20 adrenal glands seen on volumetric CT datasets for abnormality.
Year
DOI
Venue
2013
10.1007/s10278-012-9554-7
J. Digital Imaging
Keywords
Field
DocType
Adrenal glands,Abnormality detection,Random forest
Computer vision,Histogram,Abdomen,Cone beam computed tomography,Abnormality,Artificial intelligence,Radiology,Region of interest,Random forest,Hounsfield scale,Medicine,Adrenal gland
Journal
Volume
Issue
ISSN
26
5
1618-727X
Citations 
PageRank 
References 
6
0.57
8
Authors
5
Name
Order
Citations
PageRank
Ganesh Saiprasad191.03
Chein-I Chang23399429.03
Nabile Safdar3498.05
Naomi Saenz460.57
Eliot Siegel530280.13