Name
Title | ||
|---|---|---|
Cardiogoniometric parameters for detection of coronary artery disease at rest as a function of stenosis localization and distribution. |
Abstract | ||
|---|---|---|
Cardiogoniometry (CGM), a spatiotemporal electrocardiologic 5-lead method with automated analysis, may be useful in primary healthcare for detecting coronary artery disease (CAD) at rest. Our aim was to systematically develop a stenosis-specific parameter set for global CAD detection. In 793 consecutively admitted patients with presumed non-acute CAD, CGM data were collected prior to elective coronary angiography and analyzed retrospectively. 658 patients fulfilled the inclusion criteria, 405 had CAD verified by coronary angiography; the 253 patients with normal coronary angiograms served as the non-CAD controls. Study patients--matched for age, BMI, and gender--were angiographically assigned to 8 stenosis-specific CAD categories or to the controls. One CGM parameter possessing significance (P < .05) and the best diagnostic accuracy was matched to one CAD category. The area under the ROC curve was .80 (global CAD versus controls). A set containing 8 stenosis-specific CGM parameters described variability of R vectors and R-T angles, spatial position and potential distribution of R/T vectors, and ST/T segment alterations. Our parameter set systematically combines CAD categories into an algorithm that detects CAD globally. Prospective validation in clinical studies is ongoing. |
Year | DOI | Venue |
|---|---|---|
2010 | 10.1007/s11517-010-0594-1 | Med. Biol. Engineering and Computing |
Keywords | Field | DocType |
cardiogoniometry vectorcardiography r-t angle cad diagnosis depolarization-repolarization variability,roc curve,primary healthcare | CAD,Coronary artery disease,Primary health care,Internal medicine,Cardiology,Stenosis,Radiology,Vectorcardiography,Area under the roc curve,Medicine,Angiography | Journal |
Volume | Issue | ISSN |
48 | 5 | 1741-0444 |
Citations | PageRank | References |
4 | 0.63 | 2 |
Authors | ||
7 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Thomas Huebner | 1 | 12 | 1.93 |
| W M Michael Schuepbach | 2 | 4 | 0.63 |
| Andrea Seeck | 3 | 14 | 1.99 |
| Ernst Sanz | 4 | 4 | 0.63 |
| Bernhard Meier | 5 | 4 | 0.63 |
| Andreas Voss | 6 | 52 | 13.58 |
| Roland Pilgram | 7 | 27 | 3.25 |