Paper Info
Title
Analyzing SNOMED CT and HL7 terminology binding for semantic interoperability on post-genomic clinical trials.
Abstract
Current post-genomic clinical trials in cancer involve the collaboration of several institutions. Multi-centric retrospective analysis requires advanced methods to ensure semantic interoperability. In this scenario, the objective of the EU funded INTEGRATE project, is to provide an infrastructure to share knowledge and data in post-genomic breast cancer clinical trials. This paper presents the process carried out in this project, to bind domain terminologies in the area, such as SNOMED CT, with the HL7 v3 Reference Information Model ( RIM). The proposed terminology binding follow the HL7 recommendations, but should also consider important issues such as overlapping concepts and domain terminology coverage. Although there are limitations due to the large heterogeneity of the data in the area, the proposed process has been successfully applied within the context of the INTEGRATE project. An improvement in semantic interoperability of patient data from modern breast cancer clinical trials, aims to enhance the clinical practice in oncology.
Year
DOI
Venue
2013
10.3233/978-1-61499-289-9-980
Studies in Health Technology and Informatics
Keywords
Field
DocType
Semantic Interoperability,Clinical Trials,SNOMED,HL7 RIM,INTEGRATE project,Breast Neoplasm,Terminology Binding
Data mining,Information retrieval,Terminology,Clinical trial,Semantic interoperability,SNOMED CT,Medicine
Conference
Volume
ISSN
Citations 
192
0926-9630
3
PageRank 
References 
Authors
0.53
0
7
Name
Order
Citations
PageRank
Santiago Aso130.87
david perezrey213520.28
Raúl Alonso-Calvo310714.64
Antonio Rico-Diez430.87
Anca I. D. Bucur516720.83
Brecht Claerhout63911.63
Victor Maojo733353.22